ABSTRACT
@#AIM:To evaluate changes in peripapillary atrophy(PPA)and retinal in young adults with high myopia(HM)for three years.<p>METHODS:A total of 22 HM patients(<i>n</i>=32 eyes, >-9 D), 35-45y, were enrolled in this self-controlled retrospective review. The following parameters were measured at baseline and 3-year follow-up visits: area of optic nerve head(ONH); area of peripapillary atrophy(PPA); area of peripapillary chorioretinal atrophy(PCA); type of PPA; average retinal thickness(ART); and total central retinal volume(TCRV). <p>RESULTS: There were no changes in the area of ONH(<i>t</i>=0.95, <i>P</i>=0.35)between baseline and 3-year follow-up visits. In contrast, the areas of PPA and PCA were significantly greater(0.69±0.71 and 0.57±0.97mm<sup>2</sup>,respectively)at the 3-year follow-up versus baseline(<i>t</i>=-3.99, <i>P</i>=0.001 and <i>t</i>=-2.33, <i>P</i>=0.03, respectively)visits. There were no changes in the type of the PPA. ART and TCRV did not differ significantly at the 3-year follow-up versus baseline visits(<i>P</i>>0.05).<p>CONCLUSION:Increased areas of PCA and PPA are the main fundus features of HM(>-9 D)in young adults. PPA and PCA should be important morphological parameters during follow-up for HM in clinic.